Monitoring anatomical changes of individual patients using statistical process control during head-and-neck radiotherapy
چکیده مقاله :
Reduced toxicity while maintaining loco-regional control rates have been reported after reducing planning target volume (PTV) margins for head-and-neck radiotherapy (HNRT). In this context, quantifying anatomical changes to monitor patient treatment is preferred. This retrospective feasibility study investigated the application of deformable image registration (DIR) and Exponentially Weighted Moving Average (EWMA) Statistical Process Control (SPC) charts for this purpose.
Materials and methods DIR between the computed tomography for treatment planning (pCT) images of twelve patients and their daily on-treatment cone beam computed tomography (CBCT) images quantified anatomical changes during treatment. EWMA charts investigated corresponding trends. Uncertainty analysis provided 90% confidence limits which were used to confirm whether a trend previously breached a threshold.
توضیحات تکمیلی :
مقاله ISI انگلیسی اصلی سال انتشار:2019 فایل ISI انگلیسی اصلی ، با فرمت Pdf تعداد صفحات فایل ISI انگلیسی اصلی: 7 صفحه