Sample size estimation and re-estimation of cluster randomized controlled trials for real-time feedback, debriefing, and retraining system of cardiopulmonary resuscitation for out-of-hospital cardiac arrests

چکیده مقاله :
In cluster randomized controlled trials (RCTs) for emergency medical services (EMS) system, we encounter the situation that the actual cluster size and ratio of allocated patients between two groups eventually differ from those used for sample size estimation because of the nature of patient enrollment. In such trials, estimations of effect size of test intervention and intra-cluster correlation coefficient (ICC) used for sample size estimation are also difficult. To improve efficient management on clinical cluster RCTs, we need to understand the effect of such inconsistencies of the design parameters on the type I error rate and statistical power of testing.

توضیحات تکمیلی :

مقاله ISI انگلیسی اصلی
سال انتشار:2019
فایل ISI انگلیسی اصلی ، با فرمت Pdf
تعداد صفحات فایل ISI انگلیسی اصلی: 6 صفحه


نویسندگان/توضیحات : مقاله ISI سال انتشار2019 \ Akiko Kada a, ∗ ,1 , Akihiro Hirakawa a,b,1 , Fumie Kinoshita c , Yumiko Kobayashi c , Toshihiro Hatakeyama d,e , Daisuke Kobayashi e , Chika Nishiyama f , Taku Iwami
تاریخ ارسال : 1397/11/25
تعداد بازدید : 126
کلمات کلیدی : Cluster randomization Emergency medical services Intracluster correlation coefficient Sample size re-estimation
تعداد صفحات : 6
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