Pharmaceutical supply chain models: A synthesis from a systems view of operations research

چکیده مقاله :
This research evaluates reconfiguration opportunities in Pharmaceutical Supply Chains (PSC) resulting from technology interventions in manufacturing, and new, more patient-centric delivery models. A critical synthesis of the academic and practice literature is used to identify, conceptualise, analyse and categorise PSC models. From a theoretical perspective, a systems view of operations research is adopted to pro- vide insights on a broader range of OR activities, from conceptual to mathematical modelling and model solving, up to implementation. The research demonstrates that: 1) current definitions of the PSC are largely production-centric and fail to capture patient consumption, and hence healthcare outcomes; 2) most PSC mathematical models lack adequate conceptualisation of the structure and behaviour of the supply chain, and the boundary conditions that need to be considered for a given problem; 3) models do not adequately specify current unit operations or future production technology options, and are therefore unable to address the criti- cal questions around alternative product or process technologies; 4) economic evaluations are limited to direct costing, rather than systemic approaches such as supply chain costing and total cost of ownership. While current models of the PSC may help with the optimisation of specific unit operations, their theoretical benefits could be offset by the dynamics of complex upstream (supply) and downstream (dis- tribution and healthcare delivery) systems. To overcome these limitations, this research provides initial directions towards an

توضیحات تکمیلی :

مقاله ISI انگلیسی اصلی
سال انتشار:2017
فایل ISI انگلیسی اصلی ، با فرمت Pdf
تعداد صفحات فایل ISI انگلیسی اصلی: 22 صفحه

نویسندگان/توضیحات : مقاله ISI سال انتشار2017 \ Ettore Settanni ∗, TomásSeosamh Harrington, JagjitSingh Srai
تاریخ ارسال : 1397/10/24
تعداد بازدید : 128
کلمات کلیدی : Supply networks Modelling Pharmaceuticals Critical interpretative synthesis
تعداد صفحات : 22
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