A meta-analysis: Proton pump inhibitors current use and the risk of Coronavirus Infectious Disease 2019 development and its related mortality

(چکیده مقاله) :
Abstract :

The ongoing Coronavirus Infectious Disease (COVID-19) pandemic is a global health crisis that has had a magnanimous worldwide impact on all aspects of people's lives. Several observational studies investigated the relationship between Proton Pump Inhibitors use and the risk of COVID-19 development and mortality.

Aim of the Study
The aim of this meta-analysis is to investigate the association between current PPIs use and the development of COVID-19 as well as its mortality.

Methods
Pubmed, Google Scholar, ScienceDirect and medRxiv were searched until November 21, 2020 using the following keywords: proton pump inhibitors and COVID-19 as well as their related MESH terms. The studies considered in the meta-analysis were either cohort or case-control in design and adjusted for confounding factors. The quality of the studies included in this meta-analysis were assessed using the Newcastle-Ottawa Scale. In addition, a random-effects model was used to calculate the pooled Odds Ratio (ORs) and the corresponding confidence interval (95% CI). Heterogeneity was evaluated using The Cochran's Q heterogeneity test and I2 statistic.

(توضیحات تکمیلی) :

(توضیحات تکمیلی) :
Description :

مقاله ISI انگلیسی اصلی
سال انتشار: 2021
فایل ISI انگلیسی اصلی ، با فرمت Pdf
تعداد صفحات فایل ISI انگلیسی اصلی: 14 صفحه

Authors / Descriptions(نویسندگان/توضیحات): مقاله ISI سال انتشار: 2021 / نویسندگان: Ahmad Amjed Toubasi , Rand Bilal AbuAnzeh , Bann Rami Khraisat , Thuraya Nael Al-Sayegh , Saif Aldeen AlRyalat
Sent date(تاریخ ارسال) : 1400/01/12  |   4/1/2021
Number of visits(تعداد بازدید): 528
Key words (کلمات کلیدی): Human, Pandemic, Global Health, Gastroenterology, COVID-19, Proton Pump Inhibitors.
Number of pages(تعداد صفحات) : 14
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